Related Experiment Video
Updated: Jun 13, 2025

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
Published on: November 3, 2016
Presumed Perinatal Ischemic Left Middle Cerebral Artery Stroke With Cerebral Palsy, Developmental Delay, and
Harneet S Randhawa1,2, Jasneet Randhawa3,4, Karanvir S Aulakh5
1Radiology, Sassoon General Hospital, Pune, IND.
Insights
Perinatal stroke, particularly affecting the middle cerebral artery, can cause lifelong developmental issues. This case highlights the importance of recognizing subtle MRI findings in diagnosing such strokes in infants.
Area of Science:
- Neurology
- Pediatrics
- Neuroimaging
Background:
- The perinatal period presents a significant risk for hypoxic-ischemic events, leading to substantial long-term morbidity in newborns.
- Different patterns of fetal and neonatal brain injury are observed, influenced by gestational age and the severity of hypoxia/ischemia.
Abstract:
The perinatal period is a high risk for ischemic events to occur leading to lifelong morbidity. Various patterns of ischemic injury to the fetal and neonatal brain have been studied depending on gestational age as well as the degree of hypoxia/ischemia. We present a case of presumed perinatal ischemic left middle cerebral artery stroke diagnosed by magnetic resonance imaging (MRI) in a child with global developmental delay, cerebral palsy, and epilepsy. Interestingly, the typical features of middle cerebral artery stroke are often not present in perinatal strokes, and hence these are not imaged perinatally. Since studies and research into neuroplasticity and neuromodulation are current topics of interest and several research studies are being conducted, we wish to add this case to the available scientific literature.

