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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Updated: Jun 13, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Published on: May 16, 2025

36

Dermatophytic disease: A rare case report.

Sara Ez-Zaky1, Kaoutar Imrani1, Joud Boutatleb1

  • 1Central Radiology Department, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco.

Radiology Case Reports
|September 9, 2024
PubMed
Summary
This summary is machine-generated.

Dermatophytic disease, a rare orphan condition, presents challenges due to poor understanding of its pathophysiology. This case highlights its association with immune deficiency and consanguinity, emphasizing the need for further research.

Keywords:
Dermatophytic diseaseNorth AfricaTrichophyton rubrum

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Area of Science:

  • Medical Mycology
  • Dermatology
  • Rare Diseases

Background:

  • Dermatophytic disease is a rare, poorly understood orphan condition primarily seen in North Africa.
  • It is often linked to immune deficiency and high consanguinity.
  • The pathophysiology remains largely unclear.

Observation:

  • A case of a 24-year-old man with trichophytic disease caused by Trichophyton rubrum is presented.
  • The patient exhibited numerous subcutaneous nodules.
  • The disease typically manifests initially as recurrent scalp ringworm or affects hairless skin.

Findings:

  • Trichophyton rubrum was identified as the causative agent in this case.
  • The case occurred in a context of high consanguinity.
  • Commonly isolated dermatophytes in the Maghreb include T. violaceum.

Implications:

  • Current treatment regimens are not established.
  • Management strategies focus on improving immune status and antifungal use to prevent visceral dissemination.
  • Further research is needed to elucidate the pathophysiology and establish effective treatments for this rare disease.