Related Experiment Video

Updated: Jun 13, 2025

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

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Atrial Fibrillation in Hypertrophic Cardiomyopathy

Adaya Weissler-Snir1, Sara Saberi2, Timothy C Wong3

  • 1Icahn School of Medicine at Mount Sinai Medical Center, New York, New York, USA.

JACC. Advances
|September 9, 2024
PubMed

Insights

Atrial fibrillation (AF) is common in hypertrophic cardiomyopathy (HCM) and increases stroke risk. Early AF detection and management, including anticoagulation and rhythm control, are crucial for better outcomes in HCM patients.

Area of Science:

  • Cardiology
  • Electrophysiology

Background:

  • Atrial fibrillation (AF) affects over 25% of patients with hypertrophic cardiomyopathy (HCM).
  • AF in HCM signifies advanced disease, carries a high stroke risk, and can cause poorly tolerated hemodynamic changes, even when subclinical.

Purpose of the Study:

  • To emphasize the critical need for prompt diagnosis and effective management of AF in HCM patients.
  • To outline screening strategies and treatment considerations for AF in the context of HCM.

Main Methods:

  • Regular screening for AF in all HCM patients.
  • Increased screening frequency with extended ambulatory monitoring for high-risk individuals.
  • Initiation of oral anticoagulation upon AF detection.

Main Results:

  • AF in HCM is linked to significant adverse outcomes, including stroke.
  • Management involves addressing modifiable risk factors and monitoring cardiomyopathy progression.
  • Early rhythm control may prevent further left atrial remodeling.

Conclusions:

  • Prompt AF diagnosis and management are essential in HCM to mitigate adverse events.
  • Comprehensive screening and timely intervention, including anticoagulation and potential rhythm control, are key.
  • Addressing risk factors and monitoring disease progression are integral to patient care.

Keywords:
anti-coagulationatrial fibrillationhypertrophic cardiomyopathyrate controlrhythm control

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