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High-Entropy Materials for Prospective Biomedical Applications: Challenges and Opportunities
Ling Chang1, Haochuan Jing1, Chao Liu2
1International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, Institute of Microscale Optoeletronics, Shenzhen University, Shenzhen, 518060, China.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|September 9, 2024
Summary
High-entropy materials (HEMs) offer unique properties for biomedical applications. This review explores their potential in biosensing, therapeutics, and tissue engineering, highlighting advantages and challenges.
Area of Science:
- Materials Science
- Biomedical Engineering
- Nanotechnology
Background:
- High-entropy materials (HEMs) possess unique structural, chemical, and functional characteristics.
- HEMs are gaining significant attention across various scientific disciplines, particularly in the biomedical field.
Purpose of the Study:
- To summarize the fundamental concepts, properties, and preparation methods of HEMs.
- To review the current applications and development of HEMs in biomedicine.
- To prospectively discuss potential future applications of HEMs in biological fields.
Main Methods:
- Literature review and synthesis of existing research on HEMs.
- Analysis of HEM properties in relation to biomedical requirements.
- Prospective prediction of HEM applications based on current data and trends.
Main Results:
- HEMs exhibit tunable properties suitable for advanced biomedical uses.
- Current research highlights HEMs' utility in areas like drug delivery and diagnostics.
- Diverse applications are foreseen, including biosensors, antibacterial agents, therapeutics, bioimaging, and tissue engineering.
Conclusions:
- HEMs present significant potential for revolutionizing biomedical technologies.
- Further research is needed to overcome challenges in HEM development and optimization.
- This review provides guidance for researchers exploring novel HEMs for biomedical applications.

