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Decreased Body Temperature01:29

Decreased Body Temperature

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A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Temperature control during pars plana vitrectomy.

Mario R Romano1,2, Laura Barachetti3,4, Mariantonia Ferrara5,6,7

  • 1Department of Biomedical Sciences, Humanitas University, Via Rita Levi Moltalcini 4, 20072, Pieve Emanuele-Milano, Italy. mario.romano.md@gmail.com.

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|September 9, 2024
PubMed
Summary
This summary is machine-generated.

Temperature-controlled pars plana vitrectomy (PPV) shows improved functional and structural outcomes in rabbit eyes compared to conventional PPV. Intraoperative temperature management may benefit vitreoretinal surgery.

Keywords:
Heating deviceHypothermiaIntraocular temperaturePars plana vitrectomyTemperature fluctuationsTemperature-controlled pars plana vitrectomy

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Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Surgical Innovation

Background:

  • Pars plana vitrectomy (PPV) is a common ophthalmic surgical procedure.
  • Maintaining optimal intraocular conditions during PPV is crucial for patient outcomes.
  • The impact of intraoperative temperature on retinal tissue during PPV requires further investigation.

Purpose of the Study:

  • To evaluate the impact of temperature-controlled pars plana vitrectomy (PPV) on structural and functional outcomes.
  • To compare temperature-controlled PPV with conventional PPV in a rabbit eye model.
  • To assess the potential benefits of intraoperative temperature management in vitreoretinal surgery.

Main Methods:

  • Ten New Zealand White rabbits underwent temperature-controlled PPV in one eye and conventional PPV in the contralateral eye.
  • Ophthalmic examinations and electroretinography (ERG) were performed preoperatively and 1 week postoperatively.
  • Histological and immunohistochemical analyses, including GFAP and vimentin expression, were conducted on enucleated eyes.

Main Results:

  • Temperature-controlled PPV eyes showed significantly better functional outcomes, with preserved a-wave amplitude and latency compared to conventional PPV.
  • Oscillatory potential (OP) amplitude increased in temperature-controlled PPV eyes and decreased in conventional PPV eyes.
  • Fewer structural retinal alterations were observed in the temperature-controlled PPV group, with higher GFAP expression in the conventional PPV group.

Conclusions:

  • Temperature-controlled PPV demonstrated superior functional and structural outcomes compared to conventional PPV in a rabbit model.
  • Intraoperative management of intraocular temperature appears to play a beneficial role in vitreoretinal surgery.
  • These findings support the adoption of temperature-controlled techniques to improve surgical results in ophthalmology.