The Impact of a Heart Failure Clinic on Clinical Outcomes: Our Experience

Gassan Moady1, Michal De Picciotto2, Naila Aslan3

  • 1Department of Cardiology, Galilee Medical Center, Nahariya, Israel, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.

Insights

Heart failure clinics optimize medical therapy, improving outcomes. These clinics are crucial for reducing hospital readmissions in heart failure patients.

Area of Science:

  • Cardiology
  • Clinical Medicine
  • Public Health

Background:

  • Heart failure (HF) is a growing global health concern, leading to high mortality and frequent hospitalizations.
  • Guideline-directed medical therapy significantly improves outcomes, especially for heart failure with reduced ejection fraction (HFrEF).
  • Heart failure clinics aim to optimize patient medical therapy.

Purpose of the Study:

  • To evaluate the impact of a dedicated heart failure clinic on medical therapy management.
  • To assess the effect of the clinic's interventions on clinical outcomes, specifically hospital readmissions.

Main Methods:

  • Retrospective analysis of patient data from a heart failure clinic over four years.
  • Evaluation of medical therapy adherence and optimization using patient reports and clinical data.
  • Documentation of recurrent heart failure admissions and follow-up duration.

Main Results:

  • The study included 317 patients, with 62.5% having HFrEF.
  • Optimization of sodium-glucose co-transporter 2 inhibitors (SGLT2i) and mineralocorticoid receptor antagonists (MRA) reached 92% and 91%, respectively.
  • In HFrEF patients, use of angiotensin-receptor antagonist/neprilysin inhibitor increased from 22.6% to 87.9%, and SGLT2i use rose from 49.2% to 92% (P < 0.001).
  • During a median follow-up of 2.2 years, 64% of patients were readmitted for HF, but readmission rates declined over time.

Conclusions:

  • Heart failure clinics are vital for optimizing medical therapy.
  • These specialized clinics contribute to a reduction in hospital readmissions for heart failure patients.
  • Effective management in HF clinics improves patient outcomes and quality of life.
Abstract

Related Concept Videos

Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.5K
Heart Failure Drugs: &#946;-Blockers01:22

Heart Failure Drugs: β-Blockers

β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and adrenaline (ADR). They have several beneficial effects in heart failure treatment. They reduce heart rate, the force of contraction, and cardiac muscle relaxation. They also slow the atrial-ventricular conduction rate and raise the threshold for arrhythmias. The concentration of β-blockers determines their effects on bronchodilation,...
321
Heart Failure Drugs: Inotropic Agents01:26

Heart Failure Drugs: Inotropic Agents

Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
543
Heart Failure Drugs: Diuretics01:22

Heart Failure Drugs: Diuretics

Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
350
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
398
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.4K