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Contraction of a Giant Epiretinal Human Amniotic Membrane Patch Used to Manage a Highly Myopic Retinal Detachment
Abstract:
A 64-year-old highly myopic woman with macular hole retinal detachment (MHRD) in her left eye underwent vitrectomy, internal limiting membrane (ILM) peeling, and epiretinal implantation of a 4-mm diameter human amniotic membrane (hAM) patch. One month later, she developed a bullous superior RD in her right eye, associated with a huge MH and multiple posterior breaks. Vitrectomy and ILM peeling were combined with a 15-mm epiretinal hAM patch implantation. One year later, both eyes showed successful MH closure, but the right eye developed an eccentric hAM patch contraction starting 6 months postoperatively, causing a localized stable superonasal RD. [Ophthalmic Surg Lasers Imaging Retina 2025;56:50-53.].
Insights
Human amniotic membrane (hAM) patches successfully closed macular holes in both eyes of a highly myopic patient. However, the right eye experienced patch contraction leading to a stable retinal detachment.
Area of Science:
- Ophthalmology
- Regenerative Medicine
- Retinal Surgery
Background:
- Macular hole retinal detachment (MHRD) presents a significant challenge in high myopia.
- Human amniotic membrane (hAM) is explored as a potential scaffold for retinal repair.
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