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Related Concept Videos

Cellulose and Pectic Polysaccharides01:15

Cellulose and Pectic Polysaccharides

Every plant cell has a cell wall that protects the cell, provides structural support, and gives the cell shape. Cellulose, the main structural component of the plant cell wall, makes up over 30% of plant matter. It is the most abundant organic compound on earth.  Cellulose is an unbranched polysaccharide composed of linear chains of glucose molecules linked by β (1→4) glycosidic bonds.
As a cell matures, its cell wall specializes according to its type. For example, the parenchyma cells of...
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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...

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Highly Stable, Functional Hairy Nanoparticles and Biopolymers from Wood Fibers: Towards Sustainable Nanotechnology
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Responsive nanocellulose-PNIPAM millicapsules.

Maryam Hosseini1, Isaac J Gresham1, Stuart W Prescott1

  • 1School of Chemical Engineering, University of New South Wales, Sydney, NSW, Australia.

Journal of Colloid and Interface Science
|September 10, 2024
PubMed
Summary
This summary is machine-generated.

Responsive polymer-coated bacterial cellulose microcapsules offer enhanced mechanical properties and controlled release. These adaptable capsules enable efficient content exchange and scalable, sustainable manufacturing for advanced applications.

Keywords:
Active matterNanocellulosePNIPAMThermal responsive

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Area of Science:

  • Materials Science
  • Biotechnology
  • Chemical Engineering

Background:

  • Microcapsules are increasingly required to be multifunctional, integrating capabilities like controlled release, responsiveness, and movement.
  • Minimizing material usage in capsule design necessitates efficient structural and chemical strategies.
  • Sparse fiber networks coated with responsive polymers offer a potential solution for complex, low-material-usage capsules.

Purpose of the Study:

  • To develop multifunctional milli- and micro-capsules with controlled release capabilities.
  • To investigate the use of sparse fiber networks coated with responsive polymers for capsule design.
  • To create capsules with enhanced mechanical properties, responsiveness, and scalable manufacturing potential.

Main Methods:

  • Created capsules with shells from nanoscale bacterial cellulose fiber meshes.
  • Coated cellulose fibers with thermoresponsive Poly(N-isopropylacrylamide) (PNIPAM) to control permeability and response.
  • Varied polymer grafting amounts and reaction conditions to tune capsule properties.

Main Results:

  • PNIPAM coating enhanced mechanical properties, allowing large deformations and recovery.
  • Capsules exhibited thermoreversible swelling and shrinkage in response to temperature changes.
  • Swelling/shrinkage cycles drove rapid solvent convection for content exchange (seconds).

Conclusions:

  • Polymer-modified biocapsules demonstrate a pathway for sustainable and scalable manufacturing.
  • These capsules offer a versatile platform for multifunctional responsive materials.
  • The design balances complex demands with minimized material usage through efficient structural design.