Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Morphological changes in human myocardium during permanent pacing.

P Châtelain, R Adamec, J N Cox

    Virchows Archiv. A, Pathological Anatomy and Histopathology
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Discovering Salient Anatomical Landmarks by Predicting Human Gaze.

    Proceedings. IEEE International Symposium on Biomedical Imaging·2020
    Same author

    Spatio-Temporal Partitioning and Description of Full-Length Routine Fetal Anomaly Ultrasound Scans.

    Proceedings. IEEE International Symposium on Biomedical Imaging·2020
    Same author

    Expected-value bias in routine third-trimester growth scans.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2019
    Same author

    SonoEyeNet: Standardized Fetal Ultrasound Plane Detection Informed by Eye Tracking.

    Proceedings. IEEE International Symposium on Biomedical Imaging·2019
    Same author

    Detection of carbapenemase activity in Pseudomonas aeruginosa by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS).

    Journal of microbiological methods·2018
    Same author

    Effect of summer daylight exposure and genetic background on growth in growth hormone-deficient children.

    The pharmacogenomics journal·2015
    Same journal

    Three familial cases of fundic gland polyposis without polyposis coli.

    Virchows Archiv. A, Pathological anatomy and histopathology·1993
    Same journal

    Myopathy and hypertrophic cardiomyopathy with selective lysis of thick filaments.

    Virchows Archiv. A, Pathological anatomy and histopathology·1993
    Same journal

    Alpha-smooth muscle actin and other stromal markers in endometrial mucosa.

    Virchows Archiv. A, Pathological anatomy and histopathology·1993
    Same journal

    Foamy spheroid bodies in the globus pallidus and the substantia nigra pars reticulata: an investigation on regional distribution in 56 cases without neurodegenerative diseases.

    Virchows Archiv. A, Pathological anatomy and histopathology·1993
    Same journal

    Nature and significance of calcium oxalate crystals in normal human thyroid gland. A clinicopathological and immunohistochemical study.

    Virchows Archiv. A, Pathological anatomy and histopathology·1993
    Same journal

    Longitudinally oriented smooth muscle cells in rabbit arteries.

    Virchows Archiv. A, Pathological anatomy and histopathology·1993
    See all related articles

    Permanent pacing leads cause significant inflammation and scarring. Endovenous pacing leads result in less severe morphological changes compared to epimyocardial pacing leads.

    Area of Science:

    • Cardiovascular Pathology
    • Medical Device Research
    • Cardiac Electrophysiology

    Background:

    • Permanent pacemaker implantation is a common therapy for cardiac rhythm disorders.
    • Different pacing lead types are used, potentially leading to varied tissue responses.
    • Understanding morphological changes is crucial for long-term device management.

    Purpose of the Study:

    • To investigate the morphological changes in cardiac tissue associated with permanent pacing.
    • To compare the tissue response between different types of pacing leads.
    • To evaluate the impact of chronic pacing therapy on myocardial tissue.

    Main Methods:

    • Review of 74 patient cases with permanent pacing.
    • Macroscopic examination of cardiac tissue at the implantation site.

    Related Experiment Videos

  • Microscopic slide review of implantation sites when available.

    • Main Results:

    • Prominent findings included severe chronic inflammation, scarring, and myocardial response.
    • Morphological changes were significantly less pronounced with endovenous pacing leads compared to epimyocardial leads.
    • Initial implantation trauma and chronic foreign body reactions were less severe in endovenous pacing.

    Conclusions:

    • Permanent pacing therapy induces significant morphological changes in the heart.
    • Endovenous pacing leads appear to elicit a less severe foreign body reaction and chronic trauma response than epimyocardial leads.
    • These findings have implications for lead selection and long-term pacemaker patient care.