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Updated: Jun 13, 2025

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Risk factors for deep vein thrombosis of the lower extremity after total hip arthroplasty

Lin Hang1,2, Abuduwupuer Haibier1,2, Aiben Kayierhan1,2

  • 1Sixth Afliated Hospital of Xinjiang Medical University, Orthopaedic Hospital of Xinjiang Uygur Autonomous Region, No.39 Wuxing Road, Urumqi, People's Republic of China.

BMC Surgery
|September 11, 2024
PubMed

Insights

Diabetes mellitus, elevated fibrinogen, D-dimer, and INR are key risk factors for deep vein thrombosis (DVT) after total hip arthroplasty (THA). Early assessment and intervention are crucial for improving patient outcomes.

Area of Science:

  • Orthopedic Surgery
  • Vascular Medicine
  • Thrombosis Research

Background:

  • Deep vein thrombosis (DVT) is a significant complication following total hip arthroplasty (THA).
  • Identifying risk factors is crucial for effective prevention strategies and improved patient outcomes.

Purpose of the Study:

  • To investigate the independent risk factors associated with the development of DVT after THA.
  • To provide data for targeted DVT prophylaxis in THA patients.

Main Methods:

  • Retrospective analysis of 462 patients undergoing THA.
  • Comparison of demographic and clinical variables between DVT and non-DVT groups.
  • Univariate and binary logistic regression analyses to identify risk factors.

Main Results:

  • Diabetes mellitus, elevated preoperative fibrinogen, elevated preoperative D-dimer, and elevated preoperative International Normalized Ratio (INR) were identified as significant risk factors for DVT.
  • These factors were independently associated with an increased risk of DVT post-THA.

Conclusions:

  • Diabetes mellitus, elevated preoperative fibrinogen, D-dimer, and INR are independent predictors of DVT after THA.
  • Targeted screening and management of these factors are recommended to reduce DVT incidence and enhance THA success.
Abstract

Keywords:
Deep venous thrombosisHip jointRisk factorTotal hip replacement

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