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Related Experiment Videos

Polymyalgia rheumatica/giant cell arteritis in a Cambridge general practice.

V Kyle, B Silverman, A Silman

    British Medical Journal (Clinical Research Ed.)
    |August 10, 1985
    PubMed
    Summary

    This study found polymyalgia rheumatica/giant cell arteritis is more common in general practice than previously thought, affecting approximately 33 per 1000 elderly individuals. Early detection is crucial as it is a treatable condition in older adults.

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    Area of Science:

    • Rheumatology
    • Epidemiology
    • General Practice Research

    Background:

    • Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are inflammatory conditions primarily affecting individuals over 50.
    • Previous incidence and prevalence data for PMR/GCA have largely come from hospital-based studies, potentially underestimating their occurrence in the general population.

    Purpose of the Study:

    • To determine the incidence and prevalence of polymyalgia rheumatica/giant cell arteritis within a general practice setting.
    • To compare these figures with those previously reported from hospital-based studies.
    • To highlight the importance of recognizing PMR/GCA as a common, treatable disorder in the elderly.

    Main Methods:

    • A large-scale study involving 579 patients aged 65 and over in general practice.

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  • Patient ascertainment using a questionnaire administered via interview to identify both diagnosed and undiagnosed cases.
  • Comprehensive clinical and laboratory assessments for all identified patients.

    • Main Results:

    • A total of 19 patients (33 per 1000) aged 65 and over were identified with polymyalgia rheumatica/giant cell arteritis within an eight-year period.
    • The calculated annual incidence in this age group was approximately 4 per 1000.
    • The study indicates significantly higher rates of PMR/GCA in general practice compared to hospital-based studies.

    Conclusions:

    • Polymyalgia rheumatica/giant cell arteritis is more prevalent in the general population, particularly among the elderly, than previously estimated from hospital data.
    • The interview-based questionnaire proved effective in identifying both existing and new cases of PMR/GCA.
    • Increased physician awareness of the commonality of PMR/GCA in older adults is essential for timely diagnosis and treatment.