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Updated: Jun 13, 2025

Assessment of the Metabolic Profile of Primary Leukemia Cells
Published on: November 21, 2018
Leukemia cutis as an initial presentation in a case of mixed phenotype acute leukemia: a double jeopardy
Norton Stephen1, Rajashree Jeyaraman2, Bheemanathi Hanuman Srinivas2
1Department of Pathology, Jawaharlal Institute of Post Graduate Medical Education and Research Karaikal, India.
Abstract:
Leukemia cutis (LC) is defined as infiltration of the skin by leukemic cells resulting in clinically recognizable cutaneous lesions. The lesions range from violaceous papules, plaques, nodules, blisters, maculopapular rash and as erythroderma. LC can precede or happen after the presentation of leukemia. Here, we report a case of Mixed phenotype Acute leukemia (MPAL) presenting as LC (erythematous & violaceous nodules) which is a rare as well as a grave combination as it carries a worse prognosis. Here, we present a case of MPAL which presented as Leukemia Cutis proven on biopsy. The paper discusses the importance of identifying LC both in a clinical and a pathological pretext as it is important to start the Chemotherapy for MPAL at the earliest for a better outcome.
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