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Related Experiment Video

Updated: May 4, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

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Reference Database for a Novel Binocular Visual Function Perimeter: A Randomized Clinical Trial.

Vincent Michael Patella¹, Nevin W El-Nimri², John G Flanagan³

¹Department of Ophthalmology, University of Iowa Health Care, Iowa City, Iowa.

Ophthalmology Science

|September 12, 2024

Summary

This summary is machine-generated.

A new reference database was created for the TEMPO/IMOvifa automated perimeter using data from 356 healthy subjects. This database is crucial for accurately interpreting visual field test results, considering age and stimulus eccentricity.

Keywords:

10-degree field 24-degree field Perimetry Reference database Visual field

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Area of Science:

Ophthalmology
Visual Science
Medical Device Technology

Background:

Accurate interpretation of visual field (VF) tests is essential for diagnosing and monitoring eye conditions.
Novel automated perimeters require comprehensive reference databases for reliable clinical application.

Purpose of the Study:

To construct a comprehensive reference database (RDB) for the novel TEMPO/IMOvifa binocular automated perimeter.
To establish normative values for threshold visual field testing in healthy individuals.

Main Methods:

A prospective, four-site randomized clinical trial involving 356 healthy subjects across 7 age groups.
Subjects underwent binocular threshold visual field (VF) tests (24-2 and 10-2) using the TEMPO/IMOvifa perimeter under standardized conditions.
Analysis of perimetric threshold sensitivity and reference limits, considering age and stimulus eccentricity.

Main Results:

Established an RDB for the TEMPO/IMOvifa perimeter with data from 356 healthy subjects.
Mean sensitivity was 29.1 dB (24-2 test) and 32.4 dB (10-2 test).
Age-related decline in sensitivity averaged -0.06 dB/year (24-2) and -0.05 dB/year (10-2).

Conclusions:

A reference database for the TEMPO/IMOvifa perimeter was successfully established.
Interpreting threshold VF test results requires consideration of both patient age and stimulus eccentricity.
The RDB supports the clinical utility of the TEMPO/IMOvifa automated perimeter.