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The effect of salidroside on the bone and cartilage properties in broilers
Yanyan Zhang1, Xiaoli Fan1, Hongfan Ge1
1College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Poultry Science
|September 13, 2024
Summary
Dietary salidroside (SAL) supplementation significantly improved broiler chicken leg health. SAL enhanced bone and cartilage quality, promoting better bone growth and chondrocyte activity in fast-growing chickens.
Area of Science:
- Animal Science
- Veterinary Medicine
- Biochemistry
Background:
- Leg disorders are a significant welfare issue in fast-growing broiler chickens.
- Salidroside (SAL) is known to promote osteogenesis and inhibit chondrocyte apoptosis in rats, but its effects on broiler bone growth were unknown.
Purpose of the Study:
- To investigate the effects of dietary salidroside (SAL) supplementation on bone and cartilage characteristics in broiler chickens.
- To determine if SAL can improve leg health and bone quality in broilers.
Main Methods:
- Ninety-six Arbor Acres broiler chickens were divided into control and three SAL-supplemented groups (low, medium, high dose).
- Chickens were raised to 42 days, with bone and cartilage samples collected for biomechanical testing and bone metabolism analysis.
- Gene expression of osteogenic markers and extracellular matrix components were analyzed.
Main Results:
- SAL significantly increased femur and tibia dimensions (diameter, moment of inertia, area).
- SAL enhanced bone mineral density and strength (stiffness, Young's modulus, ultimate load, fracture work).
- SAL upregulated osteogenic genes (Collagen-1, RUNX2, BMP2, ALP) and maintained chondrocyte extracellular matrix homeostasis.
Conclusions:
- Dietary SAL supplementation effectively promotes leg health in broiler chickens.
- SAL improves bone and cartilage quality by enhancing chondrocyte activity and osteogenesis.
- SAL represents a potential nutritional strategy to mitigate leg disorders in broilers.
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