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Updated: Jun 13, 2025

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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Colocalised Genetic Associations Reveal Alternative Splicing Variants as Candidate Causal Links for Breast Cancer

André Besouro-Duarte1,2, Beatriz Carrasqueiro2, Sofia Sousa2

  • 1CINTESIS@RISE, Universidade do Algarve, 8005-139 Faro, Portugal.

Cancers
|September 14, 2024
PubMed
Summary

Researchers identified genetic variants affecting gene splicing in breast tissue, potentially linking them to breast cancer risk. These findings may aid in developing new biomarkers for early breast cancer detection.

Keywords:
alternative splicingbreast cancer riskcolocalisation analysisgenome-wide association studiessplice quantitative trait loci

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