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Updated: Jun 13, 2025

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Published on: October 14, 2014
Anaphylaxis after SonoVue: A Case Report and a Literature Review
David Longhino1, Alessandro Buonomo1, Maria Assunta Zocco2
1Allergy Unit, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Catholic University of Rome, 00136 Roma, Italy.
Abstract:
SonoVue (Bracco, Milan, Italy) is a drug used in ultrasonography for the purpose of increasing the echogenicity of blood or fluids by improving the signal-to-noise ratio. Background/Objectives/Methods: We described a case of anaphylaxis due to SonoVue and performed a literature review. Results and Conclusions: We reported a case of anaphylaxis secondary to the administration of SonoVue and described all the 13 literature cases. Given its widespread use and the potentially dangerous nature of the reactions it can cause, it is advisable to know how to promptly recognize fatal reactions.
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