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Updated: Jun 13, 2025

Hyperpolarized Xenon for NMR and MRI Applications
Published on: September 6, 2012
Scintillation in Liquid Xenon for Gamma-Ray Medical Imaging: From Single Time-over-Threshold to
Quentin Lainé1,2, Nicolas Beaupere2, Dingbang Cai2
1Lab-STICC, Optics Department, IMT-Atlantique, CS 83818, Cedex 3, F-29238 Brest, France.
Abstract:
In this paper, a new light event acquisition chain in a three-gamma liquid xenon prototype for medical nuclear imaging is presented. The prototype implements the Multi-Time-Over-Threshold (MTOT) method. This method surpasses the Single-Time-Over-Threshold (STOT) by precisely determining both the number of vacuum ultraviolet (VUV) photons detected by each photomultiplier tube (PMT) and their arrival times for light signal measurement. Based on both the experimental and simulated results, the MTOT method achieved a 70% improvement in reconstructing photoelectrons (PEs) and enhanced the precision of the arrival time estimation by 20-30% compared with STOT. These results will enable an upgrade of the XEMIS2 (Xenon Medical Imaging System) camera, improving its performance as the imaged activity increases.
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An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
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