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Updated: Jun 13, 2025

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
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Enhancing ketoprofen's solubility and anti-inflammatory efficacy with safe methyl-β-cyclodextrin complexation

Rajaram Rajamohan1, Eswaran Kamaraj2, Perumal Muthuraja2

  • 1School of Chemical Engineering, Yeungnam University, Gyeongsan, 38541, Republic of Korea. rajmohanau@yu.ac.kr.

Scientific Reports
|September 14, 2024
PubMed
Summary

This study created inclusion complexes (ICs) of ketoprofen (KTP) with methyl-beta-cyclodextrin (MCD) to improve drug solubility and anti-inflammatory (AI) effects. The resulting ICs showed enhanced AI and anti-arthritic (AA) activity compared to KTP alone.

Keywords:
Anti-inflammationApoptosis by cell cycle analysisInclusion complexationKetoprofenMethyl-beta-cyclodextrinSolubility enhancement

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