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Investigating the Effect of COVID-19 on Pregnancy-Induced Hypertension (HTN): A Case-Control Study

Mohadeseh Nazari Fathabad1, Rasoul Raesi2,3, Kiavash Hushmandi4

  • 1Obstetrics and Gynecology, School of Medicine, Ayatollah Kashani Hospital, Jiroft University of Medical Sciences, Jiroft, Iran.

Current Hypertension Reviews
|September 16, 2024
PubMed

Insights

COVID-19 infection may impact pregnancy-induced high blood pressure in women. While not statistically significant in this study, gestational age showed a relationship with hypertension prevalence in COVID-19 positive pregnant individuals.

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Cardiovascular Health

Background:

  • Immune suppression is linked to hypertension.
  • High blood pressure is a common comorbidity in COVID-19 patients.
  • Understanding COVID-19's impact on pregnancy-related conditions is crucial.

Purpose of the Study:

  • To investigate the effect of COVID-19 on pregnancy-induced hypertension.
  • To analyze blood pressure changes in pregnant women with and without COVID-19.
  • To identify factors influencing hypertension in pregnant women with COVID-19.

Main Methods:

  • A case-control study involving 266 pregnant women.
  • Participants were recruited from Kashani Hospital, Jiroft City (2021-2022).
  • Women were divided into COVID-19 positive (intervention) and negative (control) groups.

Main Results:

  • No statistically significant difference in systolic or diastolic blood pressure between groups (P>0.05).
  • A statistically significant relationship was found between pregnant women's age and hypertension (P<0.05).
  • No significant association between gestational age, body mass index, and hypertension (P>0.05).

Conclusions:

  • COVID-19 may influence pregnancy-induced blood pressure.
  • Gestational age is a significant factor in hypertension prevalence among pregnant women with COVID-19.
  • Further research is needed to elucidate the complex relationship between COVID-19 and maternal hypertension.
Abstract

Keywords:
COVID-19blood pressurehypertension (HTN).pandemicpregnancyrenin-angiotensin system (RAS)

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