Comprehensive Clinical Characterization of Patients Diagnosed With Dilated Cardiomyopathy: A Cross-Sectional Study

Naresh Vishwanath Iyer Murali1,2, Awais Ilyas Mohammed1,3, Sumathi Gelli4,5

  • 1General Medicine, United Lincolnshire Hospitals NHS Trust, Grantham, GBR.

Cureus
|September 16, 2024
PubMed

Insights

Dilated cardiomyopathy (DCM) affects all ages, with higher prevalence in middle-aged and elderly men. Ischemic heart disease (IHD) and diabetes are key risk factors, necessitating vigilant monitoring for better outcomes.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Cardiomyopathy is a diverse group of heart muscle diseases.
  • Dilated cardiomyopathy (DCM) involves ventricular dilation and impaired function, distinct from other cardiac conditions.
  • Limited comprehensive data exists on DCM, highlighting the need for clinical characterization.

Purpose of the Study:

  • To identify clinical characteristics of Dilated cardiomyopathy (DCM).
  • To determine contributing factors associated with DCM diagnosis.

Main Methods:

  • A two-year, hospital-based observational cross-sectional study.
  • 120 patients diagnosed with DCM were enrolled.
  • Assessment of risk factors including ischemic heart disease (IHD), diabetes mellitus, alcohol consumption, and smoking.

Main Results:

  • DCM affects all age groups, with higher prevalence in middle-aged (41.7%) and elderly (37.5%) individuals.
  • Ischemic heart disease (IHD) was the most common risk factor (75%), followed by diabetes mellitus (70.8%), alcohol use (62.5%), and smoking (41.7%).
  • Common symptoms included pedal edema, palpitations, fatigability, and exertional dyspnea.

Conclusions:

  • Dilated cardiomyopathy (DCM) requires vigilant monitoring and prompt recognition of triggers.
  • Early detection of adverse drug reactions, electrolyte imbalances, and echocardiographic changes is crucial.
  • Awareness and early intervention contribute to reduced mortality and improved symptoms in DCM patients.