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Published on: May 16, 2020
Comprehensive Clinical Characterization of Patients Diagnosed With Dilated Cardiomyopathy: A Cross-Sectional Study
Naresh Vishwanath Iyer Murali1,2, Awais Ilyas Mohammed1,3, Sumathi Gelli4,5
1General Medicine, United Lincolnshire Hospitals NHS Trust, Grantham, GBR.
Insights
Dilated cardiomyopathy (DCM) affects all ages, with higher prevalence in middle-aged and elderly men. Ischemic heart disease (IHD) and diabetes are key risk factors, necessitating vigilant monitoring for better outcomes.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Cardiomyopathy is a diverse group of heart muscle diseases.
- Dilated cardiomyopathy (DCM) involves ventricular dilation and impaired function, distinct from other cardiac conditions.
- Limited comprehensive data exists on DCM, highlighting the need for clinical characterization.
Purpose of the Study:
- To identify clinical characteristics of Dilated cardiomyopathy (DCM).
- To determine contributing factors associated with DCM diagnosis.
Main Methods:
- A two-year, hospital-based observational cross-sectional study.
- 120 patients diagnosed with DCM were enrolled.
- Assessment of risk factors including ischemic heart disease (IHD), diabetes mellitus, alcohol consumption, and smoking.
Main Results:
- DCM affects all age groups, with higher prevalence in middle-aged (41.7%) and elderly (37.5%) individuals.
- Ischemic heart disease (IHD) was the most common risk factor (75%), followed by diabetes mellitus (70.8%), alcohol use (62.5%), and smoking (41.7%).
- Common symptoms included pedal edema, palpitations, fatigability, and exertional dyspnea.
Conclusions:
- Dilated cardiomyopathy (DCM) requires vigilant monitoring and prompt recognition of triggers.
- Early detection of adverse drug reactions, electrolyte imbalances, and echocardiographic changes is crucial.
- Awareness and early intervention contribute to reduced mortality and improved symptoms in DCM patients.
Abstract:
Background The term "cardiomyopathy" encompasses a wide range of diseases with various underlying causes. Dilated cardiomyopathy (DCM) is characterized by ventricular dilation and impaired cardiac function in the absence of congenital, valvular, hypertensive, or ischemic heart disease (IHD). This study was motivated by the high prevalence of underlying DCM and chronic heart failure, coupled with a lack of comprehensive information on DCM. The primary objective of this study was to identify the clinical characteristics and contributing factors associated with individuals diagnosed with DCM. Methods A total of 120 patients with DCM were enrolled in a two-year, hospital-based observational cross-sectional study conducted within the Medicine Department of a tertiary care center. The study assessed risk factors, including IHD, diabetes mellitus, alcohol consumption, and smoking. Results DCM was observed across all age groups, though it was notably more prevalent among middle-aged individuals (n = 50, or 41.7%) and the elderly (n = 35, or 37.5%). The condition was more commonly seen in men. IHD emerged as the predominant risk factor, affecting 75% of patients (n = 90), followed by diabetes mellitus (n = 85, or 70.8%), alcohol use (n = 75, or 62.5%), and smoking (n = 50, or 41.7%). Common symptoms included pedal edema, palpitations, easy fatigability, and exertional dyspnea. Conclusion In conclusion, DCM is a critical condition that necessitates vigilant monitoring. Consistent observation of symptoms, recognition of potential triggers, and prompt identification of adverse drug reactions, electrolyte disturbances, and echocardiographic changes are essential. This awareness and early detection were responsible for the lower mortality and early symptom improvement observed in the present study group.
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