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Production and Purification of Non Replicative Canine Adenovirus Type 2 Derived Vectors
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Revolutionizing Veterinary Health with Viral Vector-Based Vaccines
Harsh Rajeshbhai Jogi1, Nabaneeta Smaraki2, Kaushal Kishor Rajak1
1Division of Biological Products, ICAR-Indian Veterinary Research Institute (ICAR-IVRI), Izatnagar, Bareilly, Uttar Pradesh 243122 India.
Indian Journal of Microbiology
|September 16, 2024
Summary
Viral vector vaccines offer a potent and stable method for preventing infectious diseases in animals. This review discusses various viral vectored vaccines crucial for veterinary applications.
Area of Science:
- Veterinary Medicine
- Immunology
- Vaccinology
Background:
- Conventional vaccines use whole pathogens, while new generations utilize genetic material for enhanced stability and potency.
- Nucleic acid-based vaccines, including mRNA, DNA plasmid, and viral vector vaccines, induce long-lasting immune responses.
- Viral vector-based vaccines are emerging as highly effective and potent platforms.
Purpose of the Study:
- To review different types of viral vectored vaccines with veterinary importance.
- To highlight the effectiveness of viral vector vaccines in veterinary medicine.
- To discuss the development of novel viral vectors for animal disease control.
Main Methods:
- Review of existing literature on viral vectored vaccines in veterinary medicine.
- Analysis of the mechanisms of viral vector-based vaccine action.
- Discussion of various viral vectors used for vaccine development.
Main Results:
- Viral vector vaccines effectively elicit both humoral and cell-mediated immune responses without adjuvants.
- Several viruses have been successfully modified to serve as vaccine vectors.
- The veterinary field is increasingly adopting viral vector technology for disease control.
Conclusions:
- Viral vector-based vaccines represent a significant advancement in veterinary disease prevention.
- Ongoing research focuses on developing novel viral vectors for broader veterinary applications.
- These vaccines offer a promising strategy for controlling important viral diseases in animals.
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