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Related Concept Videos

Genomic DNA in Prokaryotes00:46

Genomic DNA in Prokaryotes

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The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
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Nucleic Acids and Nucleotides01:20

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Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and have instructions for its functioning. The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).
Deoxyribonucleic Acid (DNA)
DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and the organelles such as chloroplasts and mitochondria....
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Prokaryotic Cells01:28

Prokaryotic Cells

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Prokaryotes are small unicellular organisms that include the domains — Archaea and Bacteria. Bacteria include many common microorganisms, such as Salmonella and E. coli, while the Archaea include extremophiles that live in harsh environments, such as volcanic springs.
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From DNA to Protein03:06

From DNA to Protein

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The flow of genetic information in cells from DNA to mRNA to protein is described by the central dogma, which states that genes specify the sequence of mRNAs, which in turn specify the sequence of amino acids making up all proteins. The decoding of one molecule to another is performed by specific proteins and RNAs. Because the information stored in DNA is so central to cellular function, it makes intuitive sense that the cell would make mRNA copies of this information for protein synthesis...
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The Central Dogma

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Karyotyping

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Next-generation Sequencing of 16S Ribosomal RNA Gene Amplicons
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SeqCode: A Nomenclatural Code for Prokaryotes.

Pushp Lata1, Vatsal Bhargava1, Sonal Gupta1

  • 1Department of Zoology, University of Delhi, Delhi, 110007 India.

Indian Journal of Microbiology
|September 16, 2024
PubMed
Summary
This summary is machine-generated.

SeqCode provides a new way to name prokaryotes using genome sequences, even for uncultured organisms. This genetic approach ensures reproducible naming and enhances communication in microbiology.

Keywords:
ICNPSeqCodeTaxonomyUncultured prokaryotes

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Area of Science:

  • Microbiology
  • Genomics
  • Nomenclature

Background:

  • The International Code of Nomenclature of Prokaryotes has limitations, as most prokaryotes are not culturable and thus ineligible for naming.
  • A significant portion of prokaryotic diversity remains uncharacterized due to the inability to isolate and culture these organisms.

Purpose of the Study:

  • To introduce SeqCode, a novel nomenclatural system for prokaryotes based on genetic information.
  • To establish a framework for the valid publication and registration of prokaryotic names derived from genomic data.

Main Methods:

  • Utilizing genome sequences (isolated, metagenome-assembled, or single-amplified) for prokaryotic name assignment.
  • Employing the SeqCode Registry for linking metadata to names and nomenclatural types.

Main Results:

  • SeqCode enables naming of prokaryotes irrespective of their culturability.
  • The system facilitates reproducible nomenclature through a centralized registration portal.

Conclusions:

  • SeqCode offers a standardized, genome-based system for prokaryotic nomenclature, addressing limitations of previous codes.
  • This approach will improve the discovery, understanding, and comparison of prokaryotes, aiding in deciphering their ecological roles.