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Coronavirus Anatomy and Its Analytical Approaches for Targeting COVID-19
Santheraleka Ramanathan1, M B Malarvili2, Subash C B Gopinath3,4,5
1School of Biomedical Engineering, Universiti Teknologi Malaysia, UTM, 81310, Skudai, Johor, Malaysia.
Abstract:
The whole world has lived in fear of the Coronavirus 2019 (COVID-19) for more than one-fourth of a year in 2020. Since then, numerous studies have been done and others are still being conducted to identify the coronavirus causal agent and determine the ideal antiviral therapies for treating this illness. Despite the fact of significant global efforts, which are being made to develop vaccines and identify therapeutic medicines, the emergence of multiple variants has rumbled the research for developing an ideal diagnostic and therapeutic tool for targeting COVID-19. A thorough anatomy of the coronavirus virus and its global dissemination is essential for healthcare initiatives, as well as for predicting and preventing new epidemics. Testing for active COVID-19 infections is a critical public health strategy for tracking the epidemic. The widespread adoption of polymerase chain reaction (PCR) and antigen rapid test assays has increased the supply of test kits. In this chapter, the significance of molecular technique to develop prognostic analytical techniques for targeting COVID-19 along with the advantages and limitations of available techniques is discussed.
Insights
The Coronavirus 2019 (COVID-19) pandemic spurred research into diagnostic and therapeutic tools. This chapter reviews molecular techniques for COVID-19 prognosis, discussing available methods and their limitations.
Area of Science:
- Virology
- Epidemiology
- Molecular Diagnostics
Background:
- The global Coronavirus 2019 (COVID-19) pandemic has necessitated rapid advancements in diagnostics and therapeutics.
- Emerging variants of SARS-CoV-2 present ongoing challenges for effective treatment and control.
- Understanding viral anatomy and dissemination is crucial for public health strategies and epidemic prediction.
Purpose of the Study:
- To discuss the significance of molecular techniques in developing prognostic analytical methods for COVID-19.
- To evaluate the advantages and limitations of current diagnostic and therapeutic approaches for COVID-19.
Main Methods:
- Review of molecular techniques, including polymerase chain reaction (PCR) and antigen rapid tests.
- Analysis of the role of molecular diagnostics in tracking the COVID-19 epidemic.
- Examination of the scientific literature on antiviral therapies and vaccine development.
Main Results:
- Widespread adoption of PCR and antigen tests has increased testing capacity.
- Molecular techniques are vital for prognostic analysis and understanding COVID-19 progression.
- Challenges remain in developing ideal diagnostic and therapeutic tools due to viral evolution.
Conclusions:
- Molecular techniques offer significant potential for prognostic analysis of COVID-19.
- A comprehensive understanding of viral characteristics and spread is essential for effective pandemic response.
- Continued research is needed to overcome limitations and develop superior diagnostic and therapeutic solutions for COVID-19.
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