Related Experiment Video
Updated: Jul 9, 2026

22:27
Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
Published on: May 6, 2010
408.8K
Hi-C/3C-seq Data Analysis for Prokaryotic Genomes with HiC-Pro
1Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, Japan. takemata.naomichi.3a@kyoto-u.ac.jp.
Methods in Molecular Biology (Clifton, N.J.)
|September 16, 2024
Abstract:
Hi-C and 3C-seq are powerful tools to study the 3D genomes of bacteria and archaea, whose small cell sizes and growth conditions are often intractable to detailed microscopic analysis. However, the circularity of prokaryotic genomes requires a number of tricks for Hi-C/3C-seq data analysis. Here, I provide a practical guide to use the HiC-Pro pipeline for Hi-C/3C-seq data obtained from prokaryotes.

