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Lipid-Laden Floret-Like Multinucleated Giant Cells: A Novel Histopathologic Observation in Rhinophyma
Maged Daruish1, Rakesh Patalay2, Eduardo Calonje1
1Department of Dermatopathology, St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom ; and.
Abstract:
Rhinophyma is the advanced stage of rosacea and manifests clinically with disfigurement of the nose. The histopathology has been classified into classical and severe types. We studied the clinicopathological characteristics of 8 cases with the diagnosis of rhinophyma. In 5 of 9 specimens, floret-like multinucleated giant cells containing lipid were identified. This finding, to the best of our knowledge, has not been previously described.
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