Related Experiment Video

Updated: May 4, 2026

Postproduction Processing of Electrospun Fibres for Tissue Engineering
15:52

Postproduction Processing of Electrospun Fibres for Tissue Engineering

Published on: August 9, 2012

18.1K

Improvement in probiotic intestinal survival by electrospun milk fat globule membrane-pullulan nanofibers:

Yucong Wang1, Zhixin Xie1, Haitian Li1

  • 1College of Food Science, Northeast Agricultural University, Harbin 150030, China.

Food Chemistry: X
|September 19, 2024
PubMed

Insights

Milk fat globule membrane (MFGM) and pullulan (PUL) fibers effectively encapsulate probiotics like Lacticaseibacillus rhamnosus GG (LGG). MFGM/PUL enhances probiotic survival in harsh conditions, showing promise for robust encapsulation applications.

Area of Science:

  • Food Science and Technology
  • Biomaterials Engineering
  • Microbiology

Background:

  • Milk fat globule membrane (MFGM) is known for protecting probiotics.
  • No prior studies have reported MFGM-based probiotic encapsulation.
  • Probiotic stability is crucial for their efficacy.

Purpose of the Study:

  • To investigate MFGM and pullulan (PUL) polysaccharide fibers for probiotic encapsulation.
  • To evaluate the properties and survival of encapsulated Lacticaseibacillus rhamnosus GG (LGG).
  • To compare MFGM/PUL encapsulation with whey protein isolates (WPI)/PUL control.

Main Methods:

  • Electrostatic spinning of MFGM/PUL and WPI/PUL solutions.
  • Characterization of morphology, physical, and mechanical properties.
  • Assessment of LGG survival in simulated intestinal conditions.

Main Results:

  • MFGM/PUL solution exhibited significant effects on pH, viscosity, conductivity, and stability.
  • Electrostatic spinning enhanced the mechanical properties and encapsulation efficiency of MFGM/PUL.
  • MFGM/PUL encapsulated LGG showed higher survival rates than WPI/PUL in mimic intestinal juice.

Conclusions:

  • MFGM is a promising biomaterial for probiotic encapsulation due to its phospholipid content.
  • MFGM/PUL nanofibers offer a robust matrix for enhanced probiotic stability.
  • This study provides a basis for utilizing MFGM/PUL nanofibers in functional food applications.
Keywords:
Electrospun fibersEncapsulationMilk fat globule membraneProbioticsPullulanWhey protein isolate

More Related Videos

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model05:41

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

2.8K
Author Spotlight: Process Development for the Spray-Drying of Probiotic Bacteria and Evaluation of the Product Quality05:45

Author Spotlight: Process Development for the Spray-Drying of Probiotic Bacteria and Evaluation of the Product Quality

Published on: April 7, 2023

3.2K

Related Concept Videos

Bacterial Flora of the Large Intestine01:29

Bacterial Flora of the Large Intestine

The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
1.7K
Probiotics01:22

Probiotics

Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
296