Related Experiment Video
Updated: Jun 12, 2025

08:02
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
3.4K
[Allergic contact dermatitis due to Furacin®]
Lucía Moreno-Lozano1, Teresa de Aramburu-Mera2, Carmen Bermúdez-Hormigo2
1Servicio de Alergología, Hospital Punta Europa, Algeciras (Cádiz), España. luciamoreloza@gmail.com.
Summary
Topical nitrofurazone, a common antibiotic, can cause allergic reactions. Patch testing identified nitrofurantoin as the allergen in a patient treated with Furacin®, highlighting the need to consider both active ingredients and excipients in adverse reactions.
Area of Science:
- Dermatology
- Allergology
- Pharmacology
Background:
- Allergic sensitization to topical antimicrobials is a recognized clinical issue.
- Furacin®, containing 0.2% nitrofurazone and polyethylene glycol (PEG) vehicle, is frequently used.
- Topical antibiotics are essential for treating skin infections.
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