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A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
A Whiff of Trouble: Navigating Allergic Contact Dermatitis to Fragrance
Ivan Rodriguez1, Madison Wolkov1, Julia Herbst1
1Ivan Rodriguez is from Keck School of Medicine, University of Southern California, Los Angeles. Madison Wolkov, Julia Herbst, and Dr. Scheman are from North Shore Center for Medical Aesthetics, Northbrook, Illinois. Dr. Scheman also is from the Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Mykayla Sandler and Dr. Yu are from the Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston. Dr. Adler is from the Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles.
Abstract:
Fragrances are found in abundance in everyday life-from obvious sources such as perfumes, colognes, and air fresheners, to not-so-common sources, such as workplace exposures. Problematically, even products labeled as "fragrance free" may contain covert fragrances. Patients and physicians alike should be aware that fragrances are a common cause of allergic contact dermatitis (ACD) and that patient education is critical to treatment success. In this review, we discuss the chemistry and epidemiology of fragrance ACD, patch test considerations, skillful patient education on avoidance, and potential pitfalls for patients with fragrance allergy-all to empower treating clinicians with the knowledge to effectively address patient needs.
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