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Correlation Between Morphological Patterns and Multidetector Computed Tomography (MDCT) Enhancement Patterns in
Anamika Meena1, Madhuri Kumari1, Rama Anand2
1Department of Radiodiagnosis, All India Institute of Medical Sciences, Patna, IND.
Cureus
|September 20, 2024
Summary
Gallbladder cancer wall thickening on CT scans correlates with locoregional infiltration. Hypo-isoenhancement is common, while intraluminal growth shows no significant association with metastasis.
Area of Science:
- Radiology
- Oncology
- Gastroenterology
Background:
- Gallbladder cancer (GBC) poses a significant health challenge, particularly in the Indian population.
- Accurate assessment of locoregional infiltration is crucial for treatment planning and prognosis.
Purpose of the Study:
- To investigate the relationship between morphological patterns and multidetector computed tomography (MDCT) enhancement patterns in Indian patients with gallbladder cancer and locoregional infiltration.
Main Methods:
- A cross-sectional study involving patients diagnosed with gallbladder disorders.
- MDCT scans were performed using a 40-slice scanner with oral contrast administration.
- Analysis focused on correlating specific CT findings like wall thickening and enhancement patterns with infiltration sites.
Main Results:
- Gallbladder wall thickening showed significant associations with infiltration into the liver, colon, bile ducts, and vascular structures.
- Portovenous hyperenhancement strongly correlated with all morphological patterns, especially hypo-isoenhancement on non-contrast CT.
- Arterial hyperenhancement exhibited an inverse relationship with certain morphological patterns.
Conclusions:
- Gallbladder cancer often results in gallbladder replacement or damage, with wall thickening being a common CT finding.
- Hypo-isoenhancement is the prevalent imaging pattern, whereas hyperenhancement is less frequent.
- While intraluminal polypoidal growth lacked significant correlation with metastasis, wall thickening emerged as a key indicator of disease spread.
