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Updated: Jun 12, 2025

Models of Bone Metastasis
Published on: September 4, 2012
Metastatic gastric adenocarcinoma discovered in the bone marrow
Ekaterina Proskuriakova1, Vaisny Balamurali2, Anuradha Hooda3
1Internal Medicine, Mount Sinai Hospital, Chicago, Illinois, USA ekaterinaproskuriakova@gmail.com.
Abstract:
Gastric cancer primarily metastasizes to the peritoneum, liver and lungs, with bone marrow involvement being a rare occurrence, found in less than 1% of cases. Disseminated carcinomatosis of the bone marrow (DCBM) is characterised by widespread infiltration of cancer cells into the bone marrow, leading to haematological disorders such as disseminated intravascular coagulation and thrombocytopenia. We present a unique case of a man in his late 50s with acute thrombocytopenia as the initial symptom, subsequently diagnosed with gastric cancer on bone marrow examination. Despite receiving chemotherapy, the patient's condition deteriorated rapidly, emphasising the challenging management and poor prognosis associated with DCBM. This case underscores the need for improved diagnostic strategies and therapeutic approaches to enhance patient outcomes in DCBM associated with gastric cancer.
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