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Updated: Jun 12, 2025

Author Spotlight: Exploring the Effects of Transauricular Vagus Nerve Stimulation
Published on: January 19, 2024
Enhancing Vagal Tone, Modulating Heart Rate Variability with Auricular Acupressure at Point Zero: A Randomized
Dieu-Thuong Thi Trinh1, Nguyen Cong Nguyen2, An Hoa Tran2,3
1Traditional Medicine Administration, Ministry of Health, Ha Noi, Vietnam.
Auricular acupressure (AA) at Point Zero significantly enhances vagal activity, as shown by improved heart rate variability (HRV) in healthy volunteers. This non-invasive technique offers a promising method for modulating autonomic function.
Area of Science:
- Neuroscience
- Integrative and Complementary Medicine
- Cardiology
Background:
- The vagus nerve plays a crucial role in regulating autonomic nervous system balance.
- Point Zero, located in the auricular branch of the vagus nerve, is a potential target for neuromodulation.
- Heart rate variability (HRV) is a reliable indicator of vagal tone and autonomic function.
Purpose of the Study:
- To investigate the effects of auricular acupressure (AA) at Point Zero on vagal activity.
- To measure changes in heart rate variability (HRV) following AA intervention.
- To assess the immediate and short-term impact of AA on autonomic function.
Main Methods:
- A single-blinded randomized controlled trial was conducted with 114 healthy volunteers.
- Participants were assigned to either the AA group (n=57) or a sham-AA (SA) group (n=57).
- HRV parameters (HR, SDNN, RMSSD, LnLF, LnHF) and respiratory rate were monitored at multiple time points before, during, and after a 30-minute intervention involving 30-second acupoint stimulations.
Main Results:
- The AA group showed significant reductions in heart rate (HR) and increases in SDNN, RMSSD, and LnHF compared to baseline and the SA group.
- These HRV improvements were most pronounced during and immediately after acupoint stimulation (T3 and T5).
- No significant changes were observed in LnLF or respiratory rate, and HR returned to baseline levels by T6, while some HRV parameters showed sustained changes.
Conclusions:
- Auricular acupressure at Point Zero can rapidly enhance vagal activity, as evidenced by HRV modulation.
- The observed effects are prompt, particularly during direct acupoint stimulation, and show some sustained changes.
- Further research is warranted to explore the long-term efficacy and therapeutic potential of AA at Point Zero for various conditions.
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