Boosting stability: a hierarchical approach for self-assembling peptide structures.

Denys Balandin1,2, Natalia Szulc3, Dominika Bystranowska4

  • 1Department of Bioorganic Chemistry, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, Wrocław 50-370, Poland. monika.szefczyk@pwr.edu.pl.

PubMed
Summary

This study enhanced peptide stability by incorporating trans-(1S,2S)-2-aminocyclopentanecarboxylic acid (trans-ACPC). This modification improved conformational stability and self-assembly in peptides with constrained beta-amino acid residues.

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