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Complete coding sequence of Tembusu virus isolate 2211-5 isolated in Taiwan
Yen-Ping Chen1, Chien-Hui Liao1, Chih-Wei Huang1
1Veterinary Research Institute, Ministry of Agriculture, New Taipei City, Taiwan.
Microbiology Resource Announcements
|September 24, 2024
Summary
Researchers identified a Tembusu virus strain in sick geese in Taiwan. This avian virus isolate is genetically similar to strains found in China, belonging to Tembusu virus Cluster 3.
Area of Science:
- Veterinary Virology
- Molecular Epidemiology
Background:
- Tembusu virus (TMUV) is an emerging flavivirus affecting various avian species.
- Recent outbreaks highlight the need for molecular characterization of circulating strains.
Purpose of the Study:
- To report the complete coding sequence of a novel Tembusu virus isolate from geese in Taiwan.
- To determine the genetic relationship of this isolate to other known TMUV strains.
Main Methods:
- Whole-genome sequencing of the Tembusu virus 2211-5 isolate from avian samples.
- Phylogenetic analysis using nucleotide sequences.
Main Results:
- The complete coding sequence of a Tembusu virus from sick geese in Taiwan (2022) was determined.
- The 2211-5 isolate showed highest nucleotide sequence similarity to the CTLN strain from China.
- The isolate was phylogenetically classified into Tembusu virus Cluster 3.
Conclusions:
- This study provides the full genetic blueprint of a Tembusu virus strain circulating in Taiwanese geese.
- The findings indicate genetic links between Tembusu virus strains in Taiwan and China, reinforcing its presence in East Asia.
