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Programmability of dual-color DNA-templated silver nanoclusters for modular design of FRET aptasensors toward
Mustafa Hussain1, Yue Liu1, Chengquan Wang2
1School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, P. R. China. wangkun@ujs.edu.cn.
Chemical Communications (Cambridge, England)
|September 25, 2024
Abstract:
By exploiting the programmability of DNA, dual-color DNA-templated silver nanoclusters have been synthesized to serve as a label-free fluorescent probe with a G5-linker at the 3' end. This advancement facilitates the modular design of universal FRET-based aptasensors using aptamers with a C5-linker at the 3' end for multiplexed detection, making them easily switch their applications.
