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Managing hypertension in older people: current concepts
James Steckelmacher1,2, Catherine Graham1,2, Carmela Maniero2,3
1Clinical Pharmacology and Precision Medicine, Queen Mary University of London William Harvey Research Institute, London, UK.
Drug and Therapeutics Bulletin
|September 25, 2024
Summary
Managing hypertension in older adults is complex due to aging, comorbidities, frailty, and polypharmacy. This review examines these challenges and evidence for effective hypertension management strategies in the elderly.
Area of Science:
- Gerontology
- Cardiovascular Medicine
- Clinical Pharmacology
Background:
- Aging leads to physiological changes impacting hypertension.
- Older adults often present with multiple comorbidities and frailty.
- Polypharmacy is common, complicating medication management.
Purpose of the Study:
- To provide an overview of challenges in hypertension management for older people.
- To review the available evidence and consensus guidance.
- To highlight clinical issues relevant to this population.
Main Methods:
- Literature review of pathophysiological changes in aging.
- Analysis of evidence base for hypertension treatments in the elderly.
- Synthesis of consensus recommendations and clinical guidelines.
Main Results:
- Age-related changes complicate hypertension.
- Evidence base for treatment in older adults is often limited.
- Clinical decision-making requires careful consideration of individual factors.
Conclusions:
- Hypertension management in older people requires a tailored approach.
- Addressing comorbidities, frailty, and polypharmacy is crucial.
- Further research is needed to strengthen the evidence base.
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