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Risk of Autism Spectrum Disorder (ASD) Among 18 to 48 Month Old Children: A Multi-Center Study in Qatar
Aisha Abdulraheem Sameea1, Ekram Wassim Abd El-Wahab2, Sherif Omar Osman2
1Hamad Medical Corporation, Doha, Qatar.
Insights
Autism screening in Qatar using the M-CHAT™ identified a prevalence of 25.13 per 10,000 children. Associated factors included older maternal age and neonatal hyperbilirubinemia.
Area of Science:
- Pediatrics
- Developmental Psychology
- Public Health
Background:
- Limited data exists on autism spectrum disorder (ASD) prevalence in Qatar.
- Inconsistent ASD screening methods contribute to varying prevalence rates globally.
- There is a need to understand ASD risk factors in the Qatari pediatric population.
Purpose of the Study:
- To conduct ASD screening among Qatari children aged 18-48 months.
- To identify factors associated with positive ASD screening results.
- To evaluate the effectiveness of the M-CHAT™ in primary healthcare settings in Qatar.
Main Methods:
- A cross-sectional study involving 600 children aged 18-48 months was conducted.
- Screening for ASD was performed using the Modified Checklist for Autism in Toddlers (M-CHAT™).
- Data was collected from 10 Primary Health Care Centers (PHCCs) across Qatar.
Main Results:
- The ASD screen-positive rate was 25.13 per 10,000 children.
- Older maternal age (10.5%) and history of neonatal hyperbilirubinemia (20.0%) were significantly associated with positive ASD screening.
- The odds of detecting ASD were lower in children under two years old (AOR=0.92).
Conclusions:
- The M-CHAT™ is a useful tool for ASD screening in Qatar's PHCCs.
- Identifying associated factors can guide future interventions for ASD in Qatar.
- Further research is needed to understand the specific risk factors within the Qatari population.
Abstract:
Background. Little is known about autism spectrum disorder (ASD) in Qatar. The lack of consensus in ASD screening has led to differences in the reported prevalence with escalating rates over time. Objective(s). To screen for ASD and to identify associate factors among Qatary children aged 18 to 48 months. Methods. A cross-sectional study included 600 eligible children at 10 Primary Health Care Centers (PHCCs) in Qatar. Identification of ASD was based on the M-CHAT™ criteria. Results. The number of ASD screen-positive children in the M-CHAT™ was 25.13 per 10.000, and was significantly associated with older maternal age (10.5%) and history of neonatal hyperbilirubinemia (20.0%) [AOR] = 4.88; 95%[CI]: 1.50-16.30)]. The Odds of detecting ASD was lower in children below 2 years of age (AOR = 0.92; 95% CI: 0.87-0.98]). Conclusion. This study demonstrates the utility of M-CHAT™ for ASD screening in PHCCs. Identification of the factors associated with positive ASD screening can highlight areas suitable for future intervention.
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