Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

495
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
495
Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

235
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
235
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

50
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
50
Neural Regulation01:37

Neural Regulation

39.2K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Practice Framework for Genetic Testing in Asymptomatic Relatives of Patients With Creutzfeldt-Jakob Disease: Experience and Insights From Israel.

European journal of neurology·2026
Same author

Prefrontal and Occipital Network Excitability Differences in Dementia with Lewy Bodies and Alzheimer's Disease.

Clinical EEG and neuroscience·2026
Same author

Correction: The association between amyloid-beta deposition on dual-task gait performance is partially moderated by cognitive functions in healthy older adults.

Scientific reports·2026
Same author

Surrounding space associations affect attentional orienting and visual discrimination in frontal field.

Scientific reports·2026
Same author

Recruitment Strategies across the Spectrum of Neuronal Synuclein Disease.

Annals of neurology·2026
Same author

Electroencephalography-Based Clustering Reveals Robust Neurophysiological Subtypes in Parkinson's Disease.

Movement disorders : official journal of the Movement Disorder Society·2026

Related Experiment Video

Updated: Jun 12, 2025

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
07:26

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Published on: September 26, 2019

7.8K

Getting oriented: Redefining attention deficits in Parkinson's disease.

Ori Peleg1, Rébaï Soret2, Pom Charras3

  • 1Laboratory for Early Markers of Neurodegeneration, Center for the Study of Movement, Cognition, and Mobility, Tel Aviv Sourasky Medical Center, Neurological Institute.

Neuropsychology
|September 26, 2024
PubMed
Summary
This summary is machine-generated.

Parkinson's disease (PD) patients show intact basic attention functions. Deficits in attention orienting emerge only when cognitive processes, like motor preparation, are needed to interpret cues.

More Related Videos

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

15.4K
Touchscreen Sustained Attention Task SAT for Rats
09:31

Touchscreen Sustained Attention Task SAT for Rats

Published on: September 15, 2017

9.8K

Related Experiment Videos

Last Updated: Jun 12, 2025

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
07:26

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Published on: September 26, 2019

7.8K
Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

15.4K
Touchscreen Sustained Attention Task SAT for Rats
09:31

Touchscreen Sustained Attention Task SAT for Rats

Published on: September 15, 2017

9.8K

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Neurology

Background:

  • Parkinson's disease (PD) impacts motor and cognitive functions, including attention.
  • Previous research focused on spatial attention in PD, but cueing format's role in attentional orienting and alerting remains underexplored.

Purpose of the Study:

  • To investigate how exogenous and endogenous cueing formats influence visuospatial attention in PD patients.
  • To assess attentional orienting benefits, reorienting costs, and alerting abilities in PD.

Main Methods:

  • Ninety PD patients and 72 healthy controls completed a spatial attention task.
  • The task involved cueing (temporal, spatial, valid, invalid) under exogenous and endogenous conditions.

Main Results:

  • PD patients showed response time benefits only for endogenous cueing requiring probabilistic prediction.
  • No significant differences were found in reorienting costs, inhibition of return, or alerting between PD patients and controls.

Conclusions:

  • Basic attentional orienting and alerting functions appear preserved in PD.
  • Attentional challenges in PD may arise when complex cognitive processes, such as motor preparation, are necessary for cue utilization.