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Updated: Jun 12, 2025

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Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure
Published on: April 17, 2018
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Fabrication of Conical Microstructure Array for Stable Droplet Generation Over Wide Flow Rate Range
Tingting Chen1, Licong Cui1, Wang He1
1School of Mechanical Engineering, Southwest Jiaotong University, Chengdu, 610031, China.
Small (Weinheim an Der Bergstrasse, Germany)
|September 27, 2024
Summary
This study presents a novel droplet generator that produces uniform droplets despite flow variations. A functional conical array regulates flow, enabling stable droplet generation for microfluidic applications.
Area of Science:
- Microfluidics
- Materials Science
- Chemical Engineering
Background:
- Droplet generators are crucial for microfluidic analysis systems.
- Flow fluctuations often lead to polydisperse droplets, hindering precise analysis.
- Achieving stable, desired-size droplet generation remains a significant challenge.
Purpose of the Study:
- To develop a high-performance droplet generator resistant to flow fluctuations.
- To investigate the mechanism of a functional conical array in droplet generation.
- To enable the production of monodisperse droplets over a wide flow range.
Main Methods:
- Fabrication of conical microstructures via selective etching of a silicon nitride/silicon substrate using potassium hydroxide (KOH).
- Integration of the conical array into the junction of microfluidic channels.
- Characterization of droplet generation performance under varying flow conditions.
Main Results:
- The conical microstructures effectively regulate the continuous phase flow rate.
- This regulation facilitates the transition to the necking phase, promoting easier droplet shedding.
- The developed droplet generator produces monodisperse droplets across a broad range of flow rates.
Conclusions:
- A novel droplet generator design utilizing a functional conical array significantly improves droplet size uniformity.
- The conical microstructures play a key role in stabilizing droplet formation by managing continuous phase flow.
- This research offers valuable insights for designing high-quality droplet generation devices for microfluidics.

