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System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
Published on: April 5, 2017
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Research on improved YOLOv8s model for detecting mycobacterium tuberculosis
Hao Chen1, Wenye Gu2, Haifei Zhang1
1School of Information Engineering, Nantong Institute of Technology, Nantong, 226002, China.
Heliyon
|September 27, 2024
Summary
This study introduces an enhanced YOLOv8s model for improved Mycobacterium tuberculosis (M. tuberculosis) detection in sputum images. The refined model achieves 85.7% average precision, aiding tuberculosis diagnosis.
Area of Science:
- Medical Imaging
- Computer Vision
- Microbiology
Background:
- Accurate identification of Mycobacterium tuberculosis (M. tuberculosis) is crucial for tuberculosis diagnosis.
- Current object detection methods face challenges with the diverse morphology and size of M. tuberculosis in sputum smear images, hindering precise localization.
Purpose of the Study:
- To develop an improved object detection model for accurate M. tuberculosis identification in sputum smear images.
- To address the limitations of existing methods in detecting M. tuberculosis with varied appearances and sizes.
Main Methods:
- An enhanced YOLOv8s model was proposed, incorporating an additional detection head for small targets.
- A multi-scale feature fusion module was introduced to handle variations in M. tuberculosis size.
- Modifications to the Coordinate Attention (CA) module, including a convolutional layer and a self-attention mechanism, were implemented to improve feature extraction and localization.
Main Results:
- The improved YOLOv8s model demonstrated strong performance on a public dataset.
- The model achieved an average precision of 85.7% for M. tuberculosis detection.
- The enhancements effectively improved the model's ability to identify M. tuberculosis with varied morphology and size.
Conclusions:
- The proposed enhanced YOLOv8s model significantly improves the accuracy of M. tuberculosis detection in sputum smear images.
- The model's effectiveness in handling morphological and size variations makes it a valuable tool for tuberculosis diagnosis.
- This work highlights the potential of advanced deep learning techniques in medical image analysis for infectious disease identification.

