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Related Concept Videos

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Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
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Radionuclide Testing
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Updated: Jan 9, 2026

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A Magnetically Controlled Capsule Robot with Biopsy Capability for Intestinal Applications.

Lingling Zheng1,2, Jie Sun1,2, Zhengdong Qi1,2

  • 1School of Information Engineering, Nanjing Xiaozhuang University, Nanjing 211171, China.

Sensors (Basel, Switzerland)
|December 11, 2025
PubMed
Summary
This summary is machine-generated.

A new magnetically controlled capsule robot for intestinal biopsy (MCCR-IB) navigates and performs biopsies. It features a magnetic locking method to separate locomotion and biopsy controls, showing promising clinical potential.

Keywords:
Intestinebiopsycapsule endoscopycapsule robotmagnetic actuationmagnetically controlled capsule robot

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Area of Science:

  • Medical Robotics
  • Gastroenterology
  • Biotechnology

Background:

  • Intestinal biopsies are crucial for diagnosing gastrointestinal diseases.
  • Current biopsy methods can be invasive and carry risks.
  • Magnetically controlled capsule robots offer a less invasive alternative for targeted interventions.

Purpose of the Study:

  • To develop and evaluate a novel Magnetically Controlled Capsule Robot for Intestinal Biopsy (MCCR-IB).
  • To address the challenge of coupled locomotion and biopsy control in capsule robots.
  • To assess the navigation and biopsy capabilities of the MCCR-IB.

Main Methods:

  • Design of the MCCR-IB with integrated locomotion and biopsy functionalities.
  • Introduction of a magnetic field locking method to decouple control systems.
  • Experimental evaluation of locomotion performance (velocity) and biopsy force.
  • Ex vivo testing to validate motion and biopsy functions.

Main Results:

  • The MCCR-IB achieved forward and backward velocities of 20.22 mm/s and 18.27 mm/s, respectively, under a 7 Hz rotating magnetic field.
  • A biopsy needle puncture force of 1.99 N was achieved.
  • Ex vivo experiments preliminarily confirmed the robot's motion and biopsy feasibility.

Conclusions:

  • The proposed MCCR-IB demonstrates effective magnetic control for intestinal navigation and biopsy.
  • The magnetic locking method successfully addresses control coupling issues.
  • The MCCR-IB shows significant potential for advancing minimally invasive gastrointestinal diagnostics and therapeutics.