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The effect of ceramides on skin absorption by Raman spectroscopy
Song Hee Kim1, Jeonghoon Yun1,2, Woncheol Kim1
1Sunjin Clinical Research Center, Sunjin Beauty Science Co., Ltd., Seoul, South Korea.
Summary
Ceramides significantly enhance skin absorption, improving moisture and barrier function. This study utilized Raman spectroscopy to demonstrate ceramides
Area of Science:
- Dermatological Science
- Cosmetics Science
- Biophysics
Background:
- Ceramides are vital for skin barrier function and moisturization.
- Their use in cosmetics is increasing, but research on skin absorption is limited.
- Understanding ceramide absorption is crucial for effective cosmetic formulations.
Purpose of the Study:
- To investigate the effect of ceramides on skin absorption using Raman spectroscopy.
- To enhance the understanding of ceramide dermatological functionality.
- To provide data supporting the topical application of ceramides in cosmetics.
Main Methods:
- Clinical trial with 20 healthy individuals with dry skin.
- Double-arm design comparing ceramide (5000 ppm) product vs. placebo.
- Raman spectroscopy used to measure skin absorption parameters.
Main Results:
- Both groups showed improved skin absorption (amount, speed, depth) (p < 0.05).
- The ceramide group demonstrated superior effectiveness in all absorption parameters compared to the control (p < 0.05).
- Raman spectroscopy provided statistically significant visual and quantitative data.
Conclusions:
- Ceramide-containing cosmetics positively impact skin absorption.
- Raman spectroscopy is a valuable tool for assessing cosmetic efficacy.
- Findings support the use of ceramides for improving skin hydration and barrier function.
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