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Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
Published on: January 5, 2024
New-Onset Chronic Musculoskeletal Pain Following COVID-19 Infection Fulfils the Fibromyalgia Clinical Syndrome
Omar Khoja1, Matthew Mulvey2, Sarah Astill3
1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds LS7 4SA, UK.
Abstract:
New-onset chronic musculoskeletal (MSK) pain (>3 months duration) is a common symptom of post-COVID-19 syndrome (PCS). This study aimed to characterise new-onset chronic MSK pain in patients with PCS and its overlap with Fibromyalgia Syndrome (FMS). We enrolled patients with new-onset chronic MSK pain post-COVID-19 and assessed the nature of the pain and associated symptoms using the C19-YRS (Yorkshire Rehabilitation Scale). The FMS assessment was conducted as part of a standard clinical examination using the American College of Rheumatology (ACR) 2010 criteria: (1) Widespread Pain Index (WPI) ≥ 7 and symptoms severity (SS) score ≥ 5, or WPI between 3 and 6 and SS score ≥ 9, (2) symptoms consistent for at least 3 months, and (3) no alternative diagnosis. Of the eighteen patients (average age 49.6 (SD 11.8) years; BMI 31.7 (SD 8.6)), twelve were female. The average symptom duration was 27.9 (SD 6.97) months post-infection. Thirteen patients (72.2%) met the FMS criteria, with an average WPI score of 8.8 and an average SS score of 8.2, indicating a high level of pain and significant quality of life impacts. These findings support the hypothesis that FMS may develop as a long-term sequela of a viral infection, underscoring the need for further research into post-viral long-term conditions.
Insights
New-onset chronic musculoskeletal pain is common in post-COVID-19 syndrome. Many patients meet criteria for Fibromyalgia Syndrome, suggesting a link between viral infections and long-term pain conditions.
Area of Science:
- Rheumatology
- Infectious Diseases
- Neurology
Background:
- Post-COVID-19 syndrome frequently includes new-onset chronic musculoskeletal pain.
- The relationship between viral infections and the development of chronic pain conditions requires further investigation.
Purpose of the Study:
- To characterize new-onset chronic musculoskeletal pain in patients with post-COVID-19 syndrome.
- To investigate the overlap between post-COVID-19 musculoskeletal pain and Fibromyalgia Syndrome (FMS).
Main Methods:
- Patients with new-onset chronic musculoskeletal pain post-COVID-19 were enrolled.
- Pain characteristics and symptoms were assessed using the Yorkshire Rehabilitation Scale (C19-YRS).
- Fibromyalgia Syndrome diagnosis was based on American College of Rheumatology 2010 criteria.
Main Results:
- Seventy-two percent of patients (13 out of 18) met the diagnostic criteria for FMS.
- Patients meeting FMS criteria reported high average Widespread Pain Index (8.8) and Symptom Severity (8.2) scores.
- The average duration of symptoms was 27.9 months post-infection.
Conclusions:
- Fibromyalgia Syndrome may develop as a long-term sequela following viral infections like COVID-19.
- These findings highlight the significant impact of post-COVID-19 musculoskeletal pain on quality of life.
- Further research into post-viral chronic pain conditions is warranted.
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