New-Onset Chronic Musculoskeletal Pain Following COVID-19 Infection Fulfils the Fibromyalgia Clinical Syndrome

Omar Khoja1, Matthew Mulvey2, Sarah Astill3

  • 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds LS7 4SA, UK.

Biomedicines
|September 28, 2024
PubMed

Insights

New-onset chronic musculoskeletal pain is common in post-COVID-19 syndrome. Many patients meet criteria for Fibromyalgia Syndrome, suggesting a link between viral infections and long-term pain conditions.

Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Neurology

Background:

  • Post-COVID-19 syndrome frequently includes new-onset chronic musculoskeletal pain.
  • The relationship between viral infections and the development of chronic pain conditions requires further investigation.

Purpose of the Study:

  • To characterize new-onset chronic musculoskeletal pain in patients with post-COVID-19 syndrome.
  • To investigate the overlap between post-COVID-19 musculoskeletal pain and Fibromyalgia Syndrome (FMS).

Main Methods:

  • Patients with new-onset chronic musculoskeletal pain post-COVID-19 were enrolled.
  • Pain characteristics and symptoms were assessed using the Yorkshire Rehabilitation Scale (C19-YRS).
  • Fibromyalgia Syndrome diagnosis was based on American College of Rheumatology 2010 criteria.

Main Results:

  • Seventy-two percent of patients (13 out of 18) met the diagnostic criteria for FMS.
  • Patients meeting FMS criteria reported high average Widespread Pain Index (8.8) and Symptom Severity (8.2) scores.
  • The average duration of symptoms was 27.9 months post-infection.

Conclusions:

  • Fibromyalgia Syndrome may develop as a long-term sequela following viral infections like COVID-19.
  • These findings highlight the significant impact of post-COVID-19 musculoskeletal pain on quality of life.
  • Further research into post-viral chronic pain conditions is warranted.

Related Concept Videos

Myocarditis II: Clinical features and Diagnostic Tests01:27

Myocarditis II: Clinical features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
2
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
95
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
903
Pericarditis II: Clinical features and Diagnostic Tests01:19

Pericarditis II: Clinical features and Diagnostic Tests

Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
3