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Updated: May 12, 2026

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
Published on: October 29, 2014
Uncommon Organisms in Neonatal Meningitis: Two Case Reports
Abstract:
These case reports describe two neonates, born at term, diagnosed with bacterial meningitis and septicemia caused by uncommon organisms. The clinical presentation, diagnostic reasoning, national guidelines, hospital course, and follow-up are discussed. Meningitis is among the differential diagnoses when there is a concern for neonatal sepsis. Concern for sepsis can arise from a variety of antepartum, intrapartum, and postpartum risk factors and present with a variety of symptoms. Neonatal sepsis is a significant cause of mortality, with 750,000 infant deaths annually. Effective treatment of neonatal sepsis requires timely diagnosis and tailored antimicrobial therapy that targets the causative pathogens.
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