Related Experiment Video

Updated: Jun 11, 2025

Generation and Culturing of Primary Human Keratinocytes from Adult Skin
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Inflammatory Mediators Suppress FGFR2 Expression in Human Keratinocytes to Promote Inflammation

Luca Ferrarese1, Michael Koch1, Artemis Baumann1

  • 1Institute of Molecular Health Sciences, Department of Biology, ETH Zürich, Zürich, Switzerland.

Molecular and Cellular Biology
|September 28, 2024
PubMed
Summary

Fibroblast Growth Factor Receptor 2 (FGFR2) deficiency in human skin cells promotes inflammation. Reduced FGFR2 in atopic dermatitis patients may worsen skin inflammation.

Keywords:
Atopic dermatitisFGFinflammationkeratinocytesignaling

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