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Updated: Jun 11, 2025

Organ Ischemia-Reperfusion Injury by Simulating Hemodynamic Changes in Rat Liver Transplant Model
Published on: March 6, 2021
Perioperative Liver and Kidney Diseases
Jeffrey W Redinger1, Kay M Johnson1, Barbara A Slawski2
1Division of General Internal Medicine, Department of Medicine, University of Washington School of Medicine, 1959 NE Pacific Street, Seattle, WA 98195, USA; Hospital and Specialty Medicine, VA Puget Sound Healthcare System, 1660 South Columbian Way (S-111-MED), Seattle, WA 98108, USA.
Abstract:
Perioperative risks associated with acute hepatitis, cirrhosis, and chronic kidney disease are substantial and prevalence of underlying chronic kidney or liver disease is rising; surgeries in these populations have accordingly become more common. Optimal perioperative management in both cases is paramount; this article focuses on understanding disease pathophysiology, a targeted preoperative evaluation, accurate estimation of perioperative risk, and anticipation and management of common postoperative complications.
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