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Updated: Jun 11, 2025
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A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
Published on: February 7, 2015
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Vascular function in multiple sclerosis: Systematic review with meta-analysis
Peixuan Zheng1, Noah G DuBose1, Sydney R DeJonge1
1Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL, USA.
Multiple Sclerosis and Related Disorders
|September 29, 2024
Summary
Individuals with multiple sclerosis (MS) exhibit poorer vascular function, particularly increased arterial stiffness, compared to healthy individuals. This highlights the need for further research into arterial stiffness in MS patients.
Area of Science:
- Neurology
- Cardiovascular Medicine
- Medical Research
Background:
- Vascular comorbidities are common in multiple sclerosis (MS).
- Underlying vascular function (VF) in MS is not well understood.
- This study systematically reviewed and meta-analyzed VF in MS versus healthy controls.
Conclusions:
- Persons with MS have demonstrably worse vascular function, especially arterial stiffness.
- Findings underscore the importance of investigating arterial stiffness in MS.
- Further research is recommended for causes, consequences, and management strategies.
