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Overview of the Vascular System

Overview of the Vascular System

The vascular system comprises an extensive network of arteries, capillaries, and veins. The vascular system can be broadly divided into the blood and lymphatic systems. Typically, blood vessels can be categorized into three histological regions: tunica intima, tunica media, and tunica adventitia. The tunica intima consists of a single layer of endothelial cells attached to the basal lamina. Underlying the basal lamina is a connective tissue layer and an elastic lamina that gives stability and...

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Updated: Jun 11, 2025

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology

Published on: February 7, 2015

Vascular function in multiple sclerosis: Systematic review with meta-analysis.

Peixuan Zheng¹, Noah G DuBose¹, Sydney R DeJonge¹

¹Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL, USA.

Multiple Sclerosis and Related Disorders

|September 29, 2024

Summary

This summary is machine-generated.

Individuals with multiple sclerosis (MS) exhibit poorer vascular function, particularly increased arterial stiffness, compared to healthy individuals. This highlights the need for further research into arterial stiffness in MS patients.

Keywords:

Arterial stiffness Arterial structure FMD Intima-media thickness Pulse wave velocity Vascular function

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Last Updated: Jun 11, 2025

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology

Published on: February 7, 2015

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

Area of Science:

Neurology
Cardiovascular Medicine
Medical Research

Background:

Vascular comorbidities are common in multiple sclerosis (MS).
Underlying vascular function (VF) in MS is not well understood.
This study systematically reviewed and meta-analyzed VF in MS versus healthy controls.

Conclusions:

Persons with MS have demonstrably worse vascular function, especially arterial stiffness.
Findings underscore the importance of investigating arterial stiffness in MS.
Further research is recommended for causes, consequences, and management strategies.