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Published on: January 29, 2016
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Depression and sedentary behaviour in women with multiple sclerosis
Eduarda F A Machado1, Felipe V Glehn2, Jeffer Sasaki3
1Universidade de Brasília, Faculdade de Educação Física, Laboratório de Análise do Movimento Humano, Brasília, Distrito Federal CEP: 70910-900, Brazil; Centro Universitário Euro-Americano, Faculdade de Medicina, Brasília, Distrito Federal, Brazil; Universidade de Rio Verde, Faculdade de Medicina, Formosa, Goiás, Brazil.
Multiple Sclerosis and Related Disorders
|September 29, 2024
Summary
Depression in women with Multiple Sclerosis (MS) is linked to increased sedentary behavior, even with similar physical activity levels. Addressing both depression and prolonged sitting is vital for MS management and preventing other health issues.
Area of Science:
- Neurology
- Psychiatry
- Public Health
Background:
- Depression is prevalent in Multiple Sclerosis (MS), affecting approximately 50% of individuals.
- People with MS (pwMS) exhibit reduced physical activity and increased sedentary behavior compared to the general population.
- Understanding depression's link with sedentary behavior in pwMS is crucial for effective therapeutic strategies.
Purpose of the Study:
- To investigate the association between depressive symptoms and sedentary behavior duration in women with relapsing-remitting MS (RRMS).
- To assess the relationship between depression, sedentary behavior, physical activity, and fatigue in women with and without MS.
Main Methods:
- A cross-sectional study involving 78 women: 38 with RRMS (EDSS 1-3) and 40 healthy controls.
- Evaluation of depression, sedentary behavior time, physical activity levels, and subjective fatigue across three groups: controls (CG), MS with depression (MSD), and MS without depression (MSND).
- Logistic regression analysis was used to determine factors associated with depression in women with MS.
Main Results:
- Women with MS and depression (MSD) exhibited significantly longer sedentary behavior durations compared to women with MS without depression (MSND).
- Depression was identified as a significant factor associated with sedentary behavior in women with MS (OR=1.62, p=0.021), even after multivariate adjustment.
- No significant differences in clinical disability (EDSS) or physical activity levels were found between MSD and MSND groups, indicating the association is independent of physical activity.
Conclusions:
- A significant relationship exists between depression and prolonged sedentary behavior in women with relapsing-remitting MS, independent of physical activity levels.
- Increased sedentary behavior in pwMS is a risk factor for comorbidities like cardiovascular disease, emphasizing the need for integrated management of depression and sedentary behavior.
- Further international research on sedentary behavior in diverse pwMS populations is essential for developing culturally tailored interventions.
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