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Diffuse unilateral MRI breast entities.

Rebecca T Sivarajah1, Trevor R Bean2, Alison L Chetlen1

  • 1Department of Radiology, Penn State Health, Hershey Medical Center, 30 Hope Drive, EC 008, Breast Center, Hershey, PA 17033, United States of America.

Clinical Imaging
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Summary
This summary is machine-generated.

Magnetic resonance imaging (MRI) can reveal diffuse unilateral breast findings for both benign and malignant conditions. Radiologists must differentiate these using MRI characteristics and clinical history for accurate diagnosis and management.

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Breast MRI clinical applicationsBreast imaging education and trainingBreast pathology

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Area of Science:

  • Radiology
  • Breast Imaging
  • Oncology

Background:

  • Diffuse unilateral findings on breast MRI can originate from various benign and malignant breast entities.
  • These findings are categorized into asymmetric diffuse masses/non-mass enhancement (NME), diffuse skin thickening, and asymmetric background enhancement.

Purpose of the Study:

  • To review common benign and malignant breast entities presenting with diffuse unilateral MRI findings.
  • To highlight key MRI features that aid in differentiating these conditions.

Main Methods:

  • Review of literature on breast MRI findings for various pathologies.
  • Analysis of MRI characteristics such as morphology, distribution, T2W signal, enhancement kinetics, and associated skin thickening.

Main Results:

  • Malignant entities include ductal carcinoma in situ, invasive ductal/lobular carcinoma, Paget disease, inflammatory, and locally advanced breast cancer.
  • Benign entities include idiopathic granulomatous mastitis (IGM), infectious mastitis, pseudoangiomatous stromal hyperplasia, giant fibroadenoma, radiation changes, breastfeeding, and central venous obstruction.

Conclusions:

  • Familiarity with diverse MRI appearances of unilateral breast findings is crucial for radiologists.
  • Accurate interpretation of MRI features, alongside clinical correlation and biopsy when necessary, ensures correct diagnosis and patient management.