Related Experiment Video
Updated: Jun 11, 2025

06:01
Fluorescence Lifetime Macro Imager for Biomedical Applications
Published on: April 7, 2023
702
Fluorescent Porous Materials Based on Aggregation-induced Emission for Biomedical Applications
Wanlu Liu1,2, Qian Liu3, Dong Wang1
1Center for AIE Research, Guangdong Provincial Key Laboratory of New Energy Materials Service Safety, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China.
ACS Nano
|September 30, 2024
Summary
Aggregation-induced emission (AIE) fluorescent porous materials offer advanced biomedical applications due to their unique properties. This review details their design, breakthroughs, and future potential in medicine.
Area of Science:
- Materials Science
- Biomedical Engineering
- Nanotechnology
Background:
- Fluorescent porous materials utilizing aggregation-induced emission (AIE) are emerging as a significant area in biomedical applications.
- These materials offer advantages such as tunable pore size, strong encapsulation, biocompatibility, and unique photophysical properties.
Purpose of the Study:
- To provide a comprehensive overview of AIE luminogen-based porous materials.
- To explore the fundamental concepts, material design, and AIE performance relationships.
- To highlight recent breakthroughs and trends in biomedical applications.
Main Methods:
- Review of inorganic, organic, and hybrid inorganic-organic porous materials.
- Analysis of structure-property relationships for AIE luminogens.
- Survey of current and emerging biomedical applications.
Main Results:
- AIE porous materials demonstrate significant potential in various biomedical fields.
- The design of these materials can be tailored to optimize AIE performance and functionality.
- Key breakthroughs in drug delivery, bioimaging, and sensing have been achieved.
Conclusions:
- AIE luminogen-based porous materials represent a rapidly advancing field with substantial biomedical promise.
- Further research into material design and application development is crucial.
- Addressing current challenges will unlock the full potential of these materials in medicine.
Related Concept Videos
Photoluminescence: Applications
381
Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
381
Reporter Genes
11.3K
Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
11.3K

